The graphic representation symbolizes the human brain. There are many small gears in the brain. In addition, you can recognize wavy lines of zeros and ones and data paths. All together, they represent the complexity and interconnectedness of the brain.

Affective disorders are common complex disorders representing one of the greatest challenges to global health in the 21st century. Advances in diagnostic precision and early targeted interventions may provide an opportunity to address the enormous public health burden and individual suffering associated with these disorders. The International Research Training Group (IRTG) 2773 “Risk Factors and Pathomechanisms of Affective Disorders” is designed as an interdisciplinary collaboration that offers a structured International Graduate Programme “Translational Research in Affective Disorders” for a new generation of talented young scientists. The IRTG is funded by Deutsche Forschungsgemeinschaft (DFG) and will start July 1st, 2022.

Multiplicity of Mechanisms: Multilevel – Multimethod Approach

Within the IRTG we aim to provide a foundation for interdisciplinary neuropsychiatric and translational research and training to elaborate and combine research methods and innovative treatment approaches for these disorders. The IRTG is embedded in the environment of the transCampus®, a unique partnership of two excellent European academic institutions – Technische Universität Dresden and King’s College London. Both institutions are leading centres in both basic research and innovative treatment of affective disorders and have pioneered the translation of results from basic science into clinical application. This expertise will be combined within the overarching aims of the IRTG to promote our key research goals:and multi-method approach in the examination of risk factors and pathomechanisms to improve early identification, understanding and treatment of affective disorders. The proposed IRTG will support the research of 10 MD students in an international environment.

  1. Investigation of risk factors and pathomechanisms of affective disorders to improve prevention, early identification and treatment
  2. Further development of the translational approach bringing basic research into clinical application and vice versa

On 5th November 2021 the DFG grants committee reached a positive final decision with funding starting on 1 July 2022. The transCampus Mental Health team will now do their utmost to facilitate a new generation of researches to learn and conduct translational clinical and neuroscientific research in an international and multidisciplinary context.

To achieve these goals we will adopt in our integrative translational research programme a multi-level/multi-method approach considering neurobiological, cognitive-emotional and social-behavioral information using state-of-the-art epidemiological, neuroscience and clinical approaches. Students of the IRTG will acquire experience in different interdisciplinary environments, enhancing their qualification for the future challenges of translational psychiatric research. Embedded in clinician scientist curricular structures, working across two leading research centres and their clinical institutions will stimulate basic research and clinical applications and provide various opportunities for translation. Our aims can ideally be accomplished by combining the complementary and interdisciplinary expertise of both transCampus® institutions that will provide a productive and interdisciplinary environment for high-level education of young scientists and prepare them for a long-term independent clinical-scientist research career.

diagram showing the curriculum for the international research training group

Research projects within the IRTG 2773: