IRTG 2251 - "Immunological and Cellular Strategies in Metabolic Disease" (ICSMD)

transCampus IRTG 2251 logo

The International Research Training Group (IRTG) 2251: "Immunological and Cellular Strategies in Metabolic Disease" (ICSMD) at the Technische Universität Dresden (TUD) and King's College London (KCL) aims at providing outstanding PhD students with a specialized but interdisciplinary programme. The collaborative training effort is exemplified by rotation of doctoral researchers to the respective partner university. The agreed tandem supervision between King’s and the TUD by two principal investigators offers the opportunity to apply for a joint PhD awarded together by the TUD and King’s (prospectus).

The goal of our research efforts is yielding in-depth insights into the pathophysiology of Type 1 and Type 2 Diabetes and development of regenerative and interventional strategies to halt, treat and even cure these pathologies. Topics addressed range from regeneration and cell replacement in Type 1 Diabetes to the immunological antigen-presenting machinery of beta cells, specific progenitor cells including new possibilities of using human pluripotent stem cells for the regeneration and/or cell preplacement of pancreatic beta-cells as well as metabolic surgery. Moreover, the IRTG aims at a better understanding of the inter-organ cross talk and immunological processes leading to peripheral insulin resistance and T2D and will advance and develop new interventional and immunological approaches and treatment options.